Allocation of distinct organ fates from a precursor field requires a shift in expression and function of gene regulatory networks
… competing with each other within the same populations of cells. We have examined the role
that the retinal determination (RD) network plays in the Drosophila eye-antennal disc… In order …
that the retinal determination (RD) network plays in the Drosophila eye-antennal disc… In order …
Drosophila Pax6 promotes development of the entire eye-antennal disc, thereby ensuring proper adult head formation
… In both cases competing developmental programs … gene regulatory networks (GRNs) are
expressed within distinct fields, thereby initiating the subdivision of the eye-antennal disc (6), …
expressed within distinct fields, thereby initiating the subdivision of the eye-antennal disc (6), …
Retinal Expression of the Drosophila eyes absent Gene Is Controlled by Several Cooperatively Acting Cis-regulatory Elements
BM Weasner, BP Weasner, SD Neuman… - PLoS …, 2016 - journals.plos.org
… of an evolutionarily conserved gene regulatory network that … In order to identify regulatory
elements that are responsive to … expression of lacZ within wild type eye-antennal discs. AEL = …
elements that are responsive to … expression of lacZ within wild type eye-antennal discs. AEL = …
Fast and Furious 800. The Retinal Determination Gene Network in Drosophila
… into the Drosophila eye (or retinal) gene regulatory network (… Drosophila eye has about 800
ommatidia, almost one order of … From L2, the eye antennal disc is bilobed. The posterior lobe …
ommatidia, almost one order of … From L2, the eye antennal disc is bilobed. The posterior lobe …
Inverse resource allocation between vision and olfaction across the genus Drosophila
… single larval structure, the eye-antennal imaginal disc. In addition, … be competing for the
same resources within a single disc (… In order to further test our hypothesis that the imaginal disc …
same resources within a single disc (… In order to further test our hypothesis that the imaginal disc …
The timing of cell fate decisions is crucial for initiating pattern formation in the Drosophila eye
BM Weasner, JP Kumar - Development, 2022 - journals.biologists.com
… The eye-antennal disc of Drosophila is composed of three cell layers: a columnar … cell layers
and/or the gene regulatory networks (GRNs) that function within them results in the failure of …
and/or the gene regulatory networks (GRNs) that function within them results in the failure of …
Eyeless/Pax6 initiates eye formation non-autonomously from the peripodial epithelium
LR Baker, BM Weasner, A Nagel, SD Neuman… - …, 2018 - journals.biologists.com
… Drosophila through studies of the gene eyeless (ey), which controls both growth of the entire
eye-antennal imaginal disc … ) network and together they activate the entire gene regulatory …
eye-antennal imaginal disc … ) network and together they activate the entire gene regulatory …
Single-cell transcriptomics in the Drosophila visual system: Advances and perspectives on cell identity regulation, connectivity, and neuronal diversity evolution
F Simon, N Konstantinides - Developmental biology, 2021 - Elsevier
… However, these concepts impose strict limitations and, in this … the inference of the gene
regulatory networks that regulate … regulatory interactions between the tTFs and the first-order …
regulatory networks that regulate … regulatory interactions between the tTFs and the first-order …
Polycomb group (PcG) proteins and Pax6 cooperate to inhibit in vivo reprogramming of the developing Drosophila eye
… de-repressed in the order of their position within the genome. In … of Pc, endogenous gene
regulatory networks (GRNs) may … eye-antennal disc, forced expression of teashirt (tsh), a gene …
regulatory networks (GRNs) may … eye-antennal disc, forced expression of teashirt (tsh), a gene …
Hippo pathway and Bonus control developmental cell fate decisions in the Drosophila eye
… develop from the larval eyeantennal disc, with the compound … However, co-IP in S2 cells
showed no competition between … of the extensive gene regulatory network that controls these …
showed no competition between … of the extensive gene regulatory network that controls these …