Allocation of distinct organ fates from a precursor field requires a shift in expression and function of gene regulatory networks

S Palliyil, J Zhu, LR Baker, SD Neuman… - PLoS …, 2018 - journals.plos.org
competing with each other within the same populations of cells. We have examined the role
that the retinal determination (RD) network plays in the Drosophila eye-antennal disc… In order

Drosophila Pax6 promotes development of the entire eye-antennal disc, thereby ensuring proper adult head formation

J Zhu, S Palliyil, C Ran… - Proceedings of the …, 2017 - National Acad Sciences
… In both cases competing developmental programs … gene regulatory networks (GRNs) are
expressed within distinct fields, thereby initiating the subdivision of the eye-antennal disc (6), …

Retinal Expression of the Drosophila eyes absent Gene Is Controlled by Several Cooperatively Acting Cis-regulatory Elements

BM Weasner, BP Weasner, SD Neuman… - PLoS …, 2016 - journals.plos.org
… of an evolutionarily conserved gene regulatory network that … In order to identify regulatory
elements that are responsive to … expression of lacZ within wild type eye-antennal discs. AEL = …

Fast and Furious 800. The Retinal Determination Gene Network in Drosophila

F Casares, I Almudi - … gene networks: Genetic control of organ formation, 2016 - Springer
… into the Drosophila eye (or retinal) gene regulatory network (… Drosophila eye has about 800
ommatidia, almost one order of … From L2, the eye antennal disc is bilobed. The posterior lobe …

Inverse resource allocation between vision and olfaction across the genus Drosophila

IW Keesey, V Grabe, L Gruber, S Koerte… - Nature …, 2019 - nature.com
… single larval structure, the eye-antennal imaginal disc. In addition, … be competing for the
same resources within a single disc (… In order to further test our hypothesis that the imaginal disc

The timing of cell fate decisions is crucial for initiating pattern formation in the Drosophila eye

BM Weasner, JP Kumar - Development, 2022 - journals.biologists.com
… The eye-antennal disc of Drosophila is composed of three cell layers: a columnar … cell layers
and/or the gene regulatory networks (GRNs) that function within them results in the failure of …

Eyeless/Pax6 initiates eye formation non-autonomously from the peripodial epithelium

LR Baker, BM Weasner, A Nagel, SD Neuman… - …, 2018 - journals.biologists.com
Drosophila through studies of the gene eyeless (ey), which controls both growth of the entire
eye-antennal imaginal disc … ) network and together they activate the entire gene regulatory

Single-cell transcriptomics in the Drosophila visual system: Advances and perspectives on cell identity regulation, connectivity, and neuronal diversity evolution

F Simon, N Konstantinides - Developmental biology, 2021 - Elsevier
… However, these concepts impose strict limitations and, in this … the inference of the gene
regulatory networks that regulate … regulatory interactions between the tTFs and the first-order

Polycomb group (PcG) proteins and Pax6 cooperate to inhibit in vivo reprogramming of the developing Drosophila eye

J Zhu, AJ Ordway, L Weber, K Buddika… - …, 2018 - journals.biologists.com
… de-repressed in the order of their position within the genome. In … of Pc, endogenous gene
regulatory networks (GRNs) may … eye-antennal disc, forced expression of teashirt (tsh), a gene

Hippo pathway and Bonus control developmental cell fate decisions in the Drosophila eye

H Zhao, KH Moberg, A Veraksa - Developmental Cell, 2023 - cell.com
… develop from the larval eyeantennal disc, with the compound … However, co-IP in S2 cells
showed no competition between … of the extensive gene regulatory network that controls these …